08613923 is referenced by 5 patents and cites 350 patents.

The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of β-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD).

Title
Monoclonal antibody
Application Number
12/213006
Publication Number
8613923 (B2)
Application Date
June 12, 2008
Publication Date
December 24, 2013
Inventor
Ryan Watts
San Mateo
CA, US
Andreas Muhs
Pully
CH
Maria Pihlgren
St. Sulpice
CH
Andrea Pfeifer
St-Légier
CH
Agent
Jones Day
Assignee
Genentech
CA, US
AC Immune
CH
IPC
A61K 38/18
C12N 5/20
C07K 16/18
A61K 39/395
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