08557244 is referenced by 35 patents and cites 103 patents.

This invention concerns methods for the treatment of intermediate and high-grade non-Hodgkins lymphomas, comprising the administration of anti-CD20 monoclonal antibodies and fragments thereof. Particular embodiments include the administration of chimeric anti-CD20 antibody, either alone or in combination with radiolabeled antibodies or chemotherapy. The invention is particularly useful for lymphomas characterized by a high number of circulating B cells, possibly bone marrow involvement, bulky disease, or the involvement of extralymphatic organs or sites.

Title
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
Application Number
9/628187
Publication Number
8557244 (B1)
Application Date
July 28, 2000
Publication Date
October 15, 2013
Inventor
Antonio Grillo Lopez
Rancho Santa Fe
CA, US
Christine White
Rancho Santa Fe
CA, US
Agent
Arnold & Porter
Ginger R Dreger
Wendy Lee
Assignee
Biogen Idec
MA, US
IPC
C07K 14/705
A61K 31/56
A61K 31/704
A61K 31/664
A61K 31/661
A61K 39/395
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