A system, method and computer-readable medium for request routing based on application information associated with the requested resource are provided. A DNS nameserver at an application broker obtains a DNS query corresponding to a resource requested from a client computing device and associated with a first resource identifier. The first resource identifier includes application information associated with the requested resource. Based on the application information parsed from the first resource identifier, the DNS nameserver at the application broker selects either a second resource identifier which resolves to a domain of a network computing provider or an IP address associated with a network computing component for processing the requested resource. The DNS nameserver then transmits either the second resource identifier or IP address to the client computing device.