08465774 is referenced by 21 patents and cites 266 patents.

Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact, such that the ratio of the mean Cmax of the antagonist after single dose oral administration of the dosage form after tampering to the mean Cmax of antagonist after single dose oral administration of an intact dosage form is at least 1.5:1.

Title
Sequestered antagonist formulations
Application Number
11/352900
Publication Number
8465774 (B2)
Application Date
February 13, 2006
Publication Date
June 18, 2013
Inventor
Curtis Wright
Norwalk
CT, US
Benjamin Oshlack
New York
NY, US
Christopher Breder
Greenwich
CT, US
Agent
Davidson Davidson & Kappel
Assignee
Purdue Pharma
CT, US
IPC
A61K 9/14
View Original Source