A multipoint lock for sliding doors. The multipoint lock mounted to a sliding door generally includes an active locking device having an active latch, and two passive locking devices, each having a passive latch. The latches are independently depth adjustable relative to an edge of the sliding door. The active locking device further includes sets of fastener apertures for receiving and securing a handle assembly thereto in at least two different positions. A lever having an actuator pin of the handling assembly can be positioned at various locations on the handle assembly such that fastener apertures of the handle assembly align with a different set of handle apertures of the active locking device depending on the position of the lever, Actuation of the active locking device by movement of the lever shifts the active latch and the passive latches simultaneously between locked and unlocked positions.