08348995 is referenced by 71 patents and cites 712 patents.

A prosthesis is provided for implantation at a native semilunar valve of a native valve complex. The prosthesis includes a distal fixation member, configured to be positioned in a downstream artery, and to apply a first axial force directed toward a ventricle. The prosthesis further includes a proximal fixation member coupled to the distal fixation member, the proximal fixation member configured to be positioned at least partially on a ventricular side of the native valve complex, and to apply a second axial force directed toward the downstream artery, such that application of the first and second forces couples the prosthesis to the native valve complex by axially sandwiching the native valve complex from a downstream side and the ventricular side. A ratio of the first axial force to a radial force applied outwardly by the prosthesis against the native semilunar valve is greater than 1.5:1. Other embodiments are also described.

Title
Axial-force fixation member for valve
Application Number
11/726875
Publication Number
8348995 (B2)
Application Date
March 23, 2007
Publication Date
January 8, 2013
Inventor
Raphael Benary
Tel Aviv
IL
Ido Kilemnik
Herzilya
IL
Yosi Tuval
Netanya
IL
Assignee
Medtronic Ventor Technologies
IL
IPC
A61F 2/24
View Original Source