08267992 is referenced by 15 patents and cites 1434 patents.

A medical implant includes a bioerodible portion that includes a bioerodible polymer and a bioerodible metal. The bioerodible polymer matrix degrades under physiological conditions to form acidic degradation products. The bioerodible metal degrades under physiological conditions to form basic degradation products. The acidic degradation products and the basic degradation products buffer at least a portion of the medical implant. In one aspect, the bioerodible portion includes a bioerodible polymer matrix and a bioerodible metal within the bioerodible polymer matrix. In another aspect, the medical implant can include a body, a plurality of discrete deposits of the bioerodible polymer on the body, and a plurality of discrete deposits of the bioerodible metal on the body.

Title
Self-buffering medical implants
Application Number
12/715577
Publication Number
8267992 (B2)
Application Date
March 2, 2010
Publication Date
September 18, 2012
Inventor
Jan Weber
Maastricht
NL
Aiden Flanagan
Co. Galway
IE
James Q Feng
Maple Grove
MN, US
Frank Genovese
Longboat
FL, US
Victor Schoenle
Greenfield
MN, US
Michael S Arney
Minneapolis
MN, US
Tom Holman
Princeton
MN, US
James Lee Shippy III
Wilmington
NC, US
Liliana Atanasoska
Edina
MN, US
Agent
Fish & Richardson P C
Assignee
Boston Scientific Scimed
MN, US
IPC
A61F 2/06
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