08227211 is referenced by 3 patents and cites 59 patents.

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.

Title
Humanized anti-CCR2 antibodies and methods of use therefor
Application Number
12/235765
Publication Number
8227211 (B2)
Application Date
September 23, 2008
Publication Date
July 24, 2012
Inventor
Theresa O Keefe
Waltham
MA, US
Siobhan H O Brien
Herts
GB
S Tarran Jones
Hertfordshire
GB
Walter Newman
Boston
MA, US
Christopher Horvath
Taunton
MA, US
Gregory J LaRosa
Newton
MA, US
Agent
Lando & Anastasi
Assignee
Millennium Pharmaceuticals
MA, US
IPC
C07K 16/00
C12N 15/13
A61K 39/395
View Original Source