08208710 is referenced by 1 patents and cites 144 patents.

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.

Title
System, method, and product for scanning of biological materials
Application Number
13/156928
Publication Number
8208710 (B2)
Application Date
June 9, 2011
Publication Date
June 26, 2012
Inventor
Ksenia Oleinik Ovod
Newton
MA, US
Joel M Katz
Stoneham
MA, US
Christopher Miles
Acton
MA, US
Roger DiPaolo
Leominster
MA, US
Eric E McKenzie
Malden
MA, US
David Bradbury
Ipswich
MA, US
Thomas P Regan
Dover
MA, US
Tim J Woolaver
Billerica
MA, US
Albert K Bukys
Lexington
MA, US
David A Stura
North Billerica
MA, US
Herman DeWeerd
Bedford
MA, US
James T Overbeck
Hingham
MA, US
Mark Jones
Reading
MA, US
Eric Schultz
North Andover
MA, US
Patrick J Odoy
Rowley
MA, US
Nathan K Weiner
Upton
MA, US
Agent
Thomas J Siepmann
Assignee
Affymetrix
CA, US
IPC
G06K 9/00
View Original Source