08206899 cites 11 patents.

The invention relates to novel nucleic acids encoding a mammalian PCADM-1 gene, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, prostate cancer. The invention further relates to methods of detecting and treating prostate cancer, comprising modulating or detecting PCADM-1 expression and/or production and activity of PCADM-1 polypeptide. Further, the invention relates to novel assays for the identification of DNA-binding proteins and the double-stranded oligonucleotide sequences that specifically bind with them. Finally, the invention relates to DNAZYMs or DNA enzymes which specifically bind PCADM-1 mRNA to inhibit PCADM-1 gene expression and thereby destroy tumor cells and tumor tissue.

Title
Prostate cancer-related compositions, methods and kits based on DNA microarray proteomics platforms
Application Number
13/11792
Publication Number
8206899 (B2)
Application Date
January 21, 2011
Publication Date
June 26, 2012
Inventor
Min Wang
Gulph Mills
PA, US
Youji Hu
Gulph Mills
PA, US
Mark Stearns
Villanova
PA, US
Agent
Riverside Law
Assignee
Philadelphia Health and Education Corporation
PA, US
IPC
G01N 33/574
G01N 33/567
G01N 33/48
G01N 1/00
C12Q 1/68
C12Q 1/00
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