08198410 is referenced by 8 patents and cites 38 patents.

This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Title
Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors
Application Number
12/277919
Publication Number
8198410 (B2)
Application Date
November 25, 2008
Publication Date
June 12, 2012
Inventor
Frank Martin
Newburty park
CA, US
Tie J Zhang
Thousand Oaks
CA, US
Heather Inoue
Oak Park
CA, US
Haichun Huang
Fremont
CA, US
James J S Treanor
Sherman Oaks
CA, US
Kenneth D Wild Jr
Simi Valley
CA, US
Agent
McDonnell Boehnen Hulbert & Berghoff
Assignee
Amgen
CA, US
IPC
C07K 16/18
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