08197409 is referenced by 94 patents and cites 155 patents.

A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

Title
Ultrasound guided high intensity focused ultrasound treatment of nerves
Application Number
12/390975
Publication Number
8197409 (B2)
Application Date
February 23, 2009
Publication Date
June 12, 2012
Inventor
James W Little
Seattle
WA, US
Shahram Vaezy
Seattle
WA, US
Jessica L Foley
Seattle
WA, US
Agent
Peter J Dehlinger
King & Spalding
Assignee
University of Washington
WA, US
IPC
A61H 1/00
A61B 8/00
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