08168652 is referenced by 3 patents and cites 28 patents.

The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.

Title
Inhibitors of AKT activity
Application Number
13/255757
Publication Number
8168652 (B2)
Application Date
March 3, 2010
Publication Date
May 1, 2012
Inventor
Kevin J Rodzinak
Schwenksville
PA, US
Mark E Layton
Harleysville
PA, US
Philip E Sanderson
Valley Forge
PA, US
Agent
David A Muthard
Yong Zhao
Matthew A Leff
Assignee
Merck Sharp & Dohme
NJ, US
IPC
C07D 471/02
A61K 31/44
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