08121365 is referenced by 1 patents and cites 232 patents.

A system and method for automatically and quantitatively determining the optimal dilution of a reagent is provided. In one embodiment of the claimed method, a plurality of dilution sets are received, where each of the dilution sets consist of a different respective dilution value and a respective plurality of immunoassay staining intensity values. A respective dynamic range metric is determining for each of the plurality of dilution sets relative to the respective plurality immunoassay staining intensity values. Having found the respective dynamic range metric, a dilution set having the numerically optimal dynamic range metric is selected and the dilution value of that dilution set is selected as being representative of an optimal dilution level of the reagent for use in a quantitative immunoassay. In one embodiment, a system is provided with a microscope, an image sensor, and processor module configured determine an optimal dilution of a reagent for use in an quantitative immunoassay.

Title
Method and system for determining an optimal dilution of a reagent
Application Number
12/188133
Publication Number
8121365 (B2)
Application Date
August 7, 2008
Publication Date
February 21, 2012
Inventor
Mark Gustavson
Niantic
CT, US
Gregory R Tedeschi
Cromwell
CT, US
Robert Pinard
New Haven
CT, US
Agent
Foley & Lardner
Daniel R Shelton
Gilberto M Villacorta
Assignee
HistoRx
CT, US
IPC
G06K 9/00
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