08106167 is referenced by 10 patents and cites 37 patents.

This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of these antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Title
Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors
Application Number
12/859246
Publication Number
8106167 (B2)
Application Date
August 18, 2010
Publication Date
January 31, 2012
Inventor
Frank Martin
Newbury Park
CA, US
Tie J Zhang
Thousand Oaks
CA, US
Heather Inoue
Oak Park
CA, US
Haichun Huang
Fremont
CA, US
James J S Treanor
Sherman Oaks
CA, US
Kenneth D Wild Jr
Simi Valley
CA, US
Agent
McDonnell Boehnen Hulbert & Berghoff
Assignee
Amgen
CA, US
IPC
C07K 16/18
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