08088616 is referenced by 65 patents and cites 548 patents.

The present technology provides for a heater substrate that contains networks of heater elements configured to controllably and selectively deliver heat to one or more PCR reaction chambers in a microfluidic substrate with which the heater substrate makes contact. In exemplary embodiments, the heater substrate can deliver heat to 12, 24, 48, or 96 chambers independently of one another, or simultaneously. The heater substrate is located in a heater unit that may be introduced into a diagnostic apparatus that can receive and position a microfluidic substrate, such as in a cartridge, in contact with the heater unit, receive one or more polynucleotide containing samples into one or more lanes in the microfluidic substrate, and cause amplification of the polynucleotides to occur, and detect presence of absence of specified polynucleotides in the amplified samples.

Title
Heater unit for microfluidic diagnostic system
Application Number
11/940315
Publication Number
8088616 (B2)
Application Date
November 14, 2007
Publication Date
January 3, 2012
Inventor
Kalyan Handique
Ypsilanti
MI, US
Agent
Knobbe Martens Olson & Bear
Assignee
HandyLab
MI, US
IPC
C12M 3/00
C12M 1/34
View Original Source