08078262 is referenced by 3 patents and cites 26 patents.

The present invention relates to methods of passive infrared imaging and dynamic infrared imaging of a tumor or lesion (“DIR”) where multiple images are taken before, during and after heating or cooling the tumor or lesion. Patterns of intensity of infrared emission in the infrared image(s) are related to the level of vascularity or metabolic activity of the tumor or lesion, and are used to identify size and shape of the tumor or lesion. The patterns can also be used to determine whether Kaposi's sarcoma lesions, skin cancer lesions and melanomas are active or inactive. Changes in the patterns of infrared emission determined by comparing images taken before, during and after the onset of drug or radiation therapy, are used to assess efficacy of the therapy. The methods can also be used to study tissue affected by angiogenic diseases.

Title
Method for imaging and spectroscopy of tumors and determination of the efficacy of anti-tumor drug therapies
Application Number
10/474977
Publication Number
8078262 (B2)
Application Date
April 15, 2002
Publication Date
December 13, 2011
Inventor
Robert Osiander
Ellicott City
MD, US
Jerry R Williams
Arlington
TX, US
John C Murphy
Clarksville
MD, US
Agent
Noah J Hayward
Assignee
The Johns Hopkins University
MD, US
IPC
A61B 6/00
View Original Source