08063050 is referenced by 25 patents and cites 96 patents.

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Title
Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
Application Number
11/773949
Publication Number
8063050 (B2)
Application Date
July 5, 2007
Publication Date
November 22, 2011
Inventor
Steven Do
San Jose
CA, US
Christine Chabot
San Mateo
CA, US
Birong Zhang
Union City
CA, US
Brian Safina
Redwood City
CA, US
Jun Liang
Palo Alto
CA, US
Anna L Banka
Longmont
CO, US
Stephen T Schlachter
Boulder
CO, US
Eli M Wallace
Lyons
CO, US
Josef R Bencsik
Longmont
CO, US
Keith Lee Spencer
Lyons
CO, US
Dengming Xiao
Longmont
CO, US
Nicholas C Kallan
Boulder
CO, US
Rui Xu
Longmont
CO, US
James F Blake
Longmont
CO, US
Ian S Mitchell
Lafayette
CO, US
Agent
Viksnins Harris & Padys PLLP
Assignee
Covenentech
CA, US
Array BioPharma
CO, US
IPC
A61P 35/00
A61K 31/496
C07D 239/70
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