08008317 is referenced by 4 patents and cites 23 patents.

The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.

Title
Inhibitors of akt activtiy
Application Number
11/921352
Publication Number
8008317 (B2)
Application Date
June 7, 2006
Publication Date
August 30, 2011
Inventor
Jiabing Wang
Chalfont
PA, US
Philip E Sanderson
Valley Forge
PA, US
Michael J Rossi
Limerick
PA, US
Kevin J Rodzinak
Schwenksville
PA, US
Jun Liang
Palo Alto
CA, US
Yiwei Li
San Diego
CA, US
Mark E Layton
Harleysville
PA, US
Michael J Kelly III
Wayne
PA, US
Essa H Hu
Camarillo
CA, US
Donna J Armstrong
Harleysville
PA, US
Agent
David A Mutard
Matthew A Leff
Assignee
Merck Sharp & Dohme
NJ, US
IPC
C07D 471/16
C07D 471/14
A61K 31/4375
A61K 31/437
View Original Source