08003651 is referenced by 22 patents and cites 96 patents.

The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Title
Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
Application Number
11/773946
Publication Number
8003651 (B2)
Application Date
July 5, 2007
Publication Date
August 23, 2011
Inventor
Christine Chabot
San Mateo
CA, US
Jun Li
Foster City
CA, US
Brian Safina
Redwood City
CA, US
Jun Liang
Palo Alto
CA, US
Anna L Banka
Longmont
CO, US
Stephen T Schlachter
Boulder
CO, US
Eli M Wallace
Lyons
CO, US
Josef R Bencsik
Longmont
CO, US
Keith Lee Spencer
Lyons
CO, US
Dengming Xiao
Longmont
CO, US
Nicholas C Kallan
Boulder
CO, US
Rui Xu
Longmont
CO, US
James F Blake
Longmont
CO, US
Ian S Mitchell
Lafayette
CO, US
Agent
Viksnins Harris & Padys PLLP
Assignee
Genertech
CA, US
Array BioPharma
CO, US
IPC
A61P 9/00
A61P 25/28
A61P 29/00
A61P 35/00
A61K 31/497
C07D 239/70
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