07969578 is referenced by 53 patents and cites 476 patents.

An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An interference is detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. Alternatively, the first electro-magnetic radiation and/or second electro-magnetic radiation have a spectrum which changes over time. The spectrum may contain multiple frequencies at a particular time. In addition, it is possible to detect the interference signal between the third radiation and the fourth radiation in a first polarization state. Further, it may be preferable to detect a further interference signal between the third and fourth radiations in a second polarization state which is different from the first polarization state. The first and/or second electro-magnetic radiations may have a spectrum whose mean frequency changes substantially continuously over time at a tuning speed that is greater than 100 Tera Hertz per millisecond.

Title
Method and apparatus for performing optical imaging using frequency-domain interferometry
Application Number
12/139314
Publication Number
7969578 (B2)
Application Date
June 13, 2008
Publication Date
June 28, 2011
Inventor
Johannes Fitzgerald De Boer
Amstelveen
NL
Guillermo J Tearney
Cambridge
MA, US
Brett E Bouma
Quincy
MA, US
Seok Hyun Yun
Cambridge
MA, US
Agent
Dorsey & Whitney
Assignee
The General Hospital Corporation
MA, US
IPC
G01B 9/02
G01B 11/02
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