07914569 is referenced by 195 patents and cites 654 patents.

A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

Title
Heart valve prosthesis and methods of manufacture and use
Application Number
11/128826
Publication Number
7914569 (B2)
Application Date
May 13, 2005
Publication Date
March 29, 2011
Inventor
Robrecht Michiels
Laguna Hills
CA, US
Stanley Komatsu
Laguna Hills
CA, US
Mykim Nguyen
Santa Ana
CA, US
Hung Nguyen
Garden Grove
CA, US
Than Nguyen
Placentia
CA, US
Agent
Mike Jaro
William L Haynes
Assignee
Medtronics CoreValve
MN, US
IPC
A61F 2/24
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