07875460 is referenced by 9 patents and cites 31 patents.

A method for determining the available treatment dosage of stabilized chlorine dioxide in the prevention and the treatment of plaque accumulation, volatile sulfur compound production, gingivitis and periodontitis, and for differentiating the treatment dosage from other chlorine-containing compounds that may not have such beneficial effects is disclosed. When in solution as stabilized chlorine dioxide, the presence of other ions such as chlorate and chloride may not only obscure results as to the concentration of stabilized ClO2, but also reduce the predicted effectiveness. The present invention uses validated analytical methods to predict the effectiveness of stabilized ClO2 by more precisely measuring its concentration in solution. Such measurement renders precision at a level required of food-grade and pharmacy-grade chemotherapeutic agents in the oral cavity. Preferred concentrations are within the range of about 0.005 to about 2% (w/v) stabilized chlorine dioxide. The solution may be in the form of wash, rinse, soak, paste, gel, aerosol spray, or other suitable delivery system.

Title
Method for determining the effectiveness of stabilized chlorine dioxide in a mouth rinse
Application Number
11/774789
Publication Number
7875460 (B2)
Application Date
July 9, 2007
Publication Date
January 25, 2011
Inventor
Jessica K Ward
Tempe
AZ, US
Elizabeth A Renken
Peoria
AZ, US
James L Ratcliff
Pueblo West
CO, US
Agent
The von Hellens Law Firm
Assignee
Micropure
AZ, US
IPC
G01N 1/18
G01N 30/90
C01B 11/02
G01N 30/02
G01N 33/00
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