07799191 is referenced by 4 patents and cites 14 patents.

The present invention provides a polymer membrane enhanced with cured epoxy resin for use as the outer membrane of biosensors. The membrane includes approximately 30-80% epoxy resin adhesives, 10-60% polymer such as poly(vinyl chloride), polycarbonate and polyurethane and 0-30% plasticizers and 5-15% surface modifier reagent such as polyethylene oxide-containing block copolymers. Utilizing the polymer membrane of the present invention, a three-layered sensing element has been developed. This sensing element will be particularly useful for miniaturized biosensors used for in vitro blood measurements or for continuous in vivo monitoring such as implantable biosensors. This element includes an enzyme layer, an interference-eliminating layer and the novel polymer member of the present invention as the outer polymer layer. This novel sensing element shows excellent response characteristics in solutions and has an extremely long lifetime. This technology is particularly useful for improving the lifetime of implantable biosensors.

Title
Epoxy enhanced polymer membrane to increase durability of biosensors
Application Number
12/15614
Publication Number
7799191 (B2)
Application Date
January 17, 2008
Publication Date
September 21, 2010
Inventor
Francis Moussy
Tampa
FL, US
Bazhang Yu
Tampa
FL, US
Agent
Smith & Hopen P A
Michele L Lawson
Assignee
University of South Florida
FL, US
IPC
G01N 33/50
C12Q 1/00
C08L 63/00
B32B 27/38
C25B 9/02
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