07741286 is referenced by 4 patents and cites 115 patents.

Modified anti-angiogenic peptides are disclosed. The modified peptides are capable of forming a peptidase stabilized anti-angiogenic peptide. The modified anti-angiogenic peptides, particularly modified kringle 5 peptides are capable of forming a conjugate with a blood protein. Conjugates are prepared from anti-angiogenic peptides, particularly kringle 5 peptides, by combining the peptide with a reactive functional group with a blood protein. The conjugates may be formed in vivo or ex vivo. The conjugates are administered to patients to provide an anti-angiogenic effect.

Title
Long lasting anti-angiogenic peptides
Application Number
11/350703
Publication Number
7741286 (B2)
Application Date
February 8, 2006
Publication Date
June 22, 2010
Inventor
Richard Beliveau
Verdun
CA
Xicai Huang
Kirkland
CA
Karen Thibaudeau
Montreal
CA
Michele Rasamoelisolo
Montreal
CA
Dominique P Bridon
San Francisco
CA, US
Agent
Jones Day
Assignee
ConjuChem Biotechnologies
CA
IPC
A61K 38/00
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