07689022 is referenced by 31 patents and cites 140 patents.

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.

Title
System, method, and product for scanning of biological materials
Application Number
10/389194
Publication Number
7689022 (B2)
Application Date
March 14, 2003
Publication Date
March 30, 2010
Inventor
Ksenia Oleink Ovod
Newton
MA, US
Joel Katz
Stoneham
MA, US
Christopher Miles
Acton
MA, US
Roger DiPaolo
Leominster
MA, US
Eric Earl McKenzie
Dunstable
MA, US
David Bradbury
Ipswich
MA, US
Thomas P Regan
Dover
MA, US
Tim Woolaver
Billerica
MA, US
Albert Bukys
Lexington
MA, US
David A Stura
North Billerica
MA, US
Herman Deweerd
Bedford
MA, US
James Overbeck
Hingham
MA, US
Mark Jones
Reading
MA, US
Erik Schultz
North Andover
MA, US
Patrick J Odoy
Rowley
MA, US
Nathan K Weiner
Upton
MA, US
Agent
Thomas J Siepmann
Assignee
Affymetrix
CA, US
IPC
G06K 9/00
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