07632859 is referenced by 3 patents and cites 130 patents.

By using a composition comprising rotigotine and at least one chloride salt in a concentration of 1 to 140 mmol/l, the composition having a pH of 4 to 6.5 in a iontophoretic device for the treatment of Parkinson's disease, it became possible to obtain a rotigotine flux across the human stratum corneum which was higher than the one previously obtained with conventional passive diffusion systems.

Title
Iontophoretic delivery of rotigotine for the treatment of Parkinsons disease
Application Number
10/713424
Publication Number
7632859 (B2)
Application Date
November 17, 2003
Publication Date
December 15, 2009
Inventor
Akhmad Karis Nugroho
Leiden
NL
Hans Michael Wolff
Monheim
DE
Johanna Aaltje Bouwstra
Barendrecht
NL
Gai Ling Li
Middlesex
GB
Agent
Harness Dickey & Pierce
Assignee
Schwarz Pharma
DE
IPC
A61N 1/30
A61K 31/38
A01N 43/06
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