07608600 is referenced by 70 patents and cites 372 patents.

2′ and/or 3′ prodrugs of 1′, 2′, 3′ or 4′-branched nucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.

Title
infections
Modified 2′ and 3′-nucleoside prodrugs for treating
Application Number
10/608907
Publication Number
7608600 (B2)
Application Date
June 27, 2003
Publication Date
October 27, 2009
Inventor
Paola LaColla
Cagliari
IT
Jean Pierre Sommadossi
Cambridge
MA, US
Gilles Gosselin
Monpellier
FR
Richard Storer
Folkstone
GB
Agent
Jones Day
Assignee
L Universite Montfellier II
FR
Centre National de la Recherche Scientifique
FR
University of Cagliari
IT
Idenix Pharmaceuticals
MA, US
IPC
A61K 31/70
A01N 43/04
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