07601818 is referenced by 22 patents and cites 37 patents.

This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.

Title
Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors
Application Number
10/891658
Publication Number
7601818 (B2)
Application Date
July 15, 2004
Publication Date
October 13, 2009
Inventor
Frank Martin
Newbury Park
CA, US
Tie J Zhang
Thousand Oaks
CA, US
Heather Inoue
Oak Park
CA, US
Haichun Huang
Fremont
CA, US
James J S Treanor
Sherman Oaks
CA, US
Kenneth D Wild Jr
Simi Valley
CA, US
Agent
McDonnell Boehnen Hulbert & Berghoff
Assignee
Medarex
NJ, US
Amgen
CA, US
IPC
C12N 5/06
C01H 21/04
G01N 33/53
C12P 21/04
A61K 39/395
C12P 21/08
C07K 16/00
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