07587238 is referenced by 100 patents and cites 129 patents.

Methods and devices for delivering cardiac therapy to a patient are provided. Various implantable device embodiments comprise a plurality of leads and a controller. The leads include at least one lead to be positioned within a lead path to deliver ventricular pacing pulses and to deliver neural stimulation at a site proximate to the heart to inhibit sympathetic nerve activity. The controller controls delivery of the ventricular pacing pulses in accordance with a programmed pacing mode and controls delivery of the neural stimulation. The controller is programmed to deliver remodeling control therapy (RCT) by delivering ventricular pacing to pre-excite a ventricular myocardium region to mechanically unload that region during systole, and further is programmed to deliver anti-remodeling therapy (ART) by delivering neural stimulation to inhibit sympathetic nerve activity in conjunction with RCT. Other embodiments are provided herein.

Title
Combined neural stimulation and cardiac resynchronization therapy
Application Number
11/78460
Publication Number
7587238 (B2)
Application Date
March 11, 2005
Publication Date
September 8, 2009
Inventor
Imad Libbus
St. Paul
MN, US
Bruce H KenKnight
Maple Grove
MN, US
Sophia Wang
New Brighton
MN, US
Julia Moffitt
North Liberty
IA, US
Agent
Schwegman Lundberg & Woessner P A
Assignee
Cardiac Pacemakers
MN, US
IPC
A61N 1/00
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