07517670 is referenced by 35 patents and cites 29 patents.

The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that includes a region equivalent to the Fc region of an immunoglobulin, with enhanced Fc-mediated cellular cytotoxicity.

Title
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
Application Number
10/633697
Publication Number
7517670 (B2)
Application Date
August 5, 2003
Publication Date
April 14, 2009
Inventor
M Sean Bailey legal representative
Santa Monica
CA, US
Joël Jean Mairet
Zürich
CH
Pablo Umaña
Zürich
CH
Agent
Sterne Kessler Goldstein & Fox PLLC
Assignee
GlycArt Biotechnology
IPC
A61K 39/00
C12N 15/63
C12N 15/12
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