07494659 is referenced by 12 patents and cites 3 patents.

The invention relates to a simple and efficient process for isolating viruses from various sources and for producing live attenuated influenza vaccines in a serum-free Vero cell culture under conditions where alterations in the surface antigens of the virus due to adpative selection are minimized or prevented. The process does not require purification of the virus-containing supernatant harvested from the cell culture nor post-incubation treatment of the viruses for HA activation. The invention further relates to influenza A and B master strain candidates and to vaccines made thereof.

Title
Live attenuated influenza vaccine
Application Number
10/381530
Publication Number
7494659 (B2)
Application Date
September 25, 2001
Publication Date
February 24, 2009
Inventor
Dietmar Katinger
Vienna
AT
Julia Romanova
Vienna
AT
Boris Ferko
Wiener Neudorf
AT
Andre Egorov
Vienna
AT
Hermann Katinger
Vienna
AT
Agent
Ostrolenk Faber Gerb & Soffen
Assignee
Polymun Scientific Immunbiologische Forschung
AT
IPC
C12N 7/00
A61K 39/145
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