07488490 is referenced by 48 patents and cites 310 patents.

The present invention relates generally to adjuvants, and in particular to methods and products utilizing a synergistic combination of immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) and a non-nucleic acid adjuvant. Such combinations of adjuvants may be used with an antigen or alone. The present invention also relates to methods and products utilizing immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) for induction of cellular immunity in infants.

Title
Method of inducing an antigen-specific immune response by administering a synergistic combination of adjuvants comprising unmethylated CpG-containing nucleic acids and a non-nucleic acid adjuvant
Application Number
10/23909
Publication Number
7488490 (B2)
Application Date
December 18, 2001
Publication Date
February 10, 2009
Inventor
Arthur M Krieg
Wellesley
MA, US
Joachim Schorr
Hilden
DE
Heather L Davis
Ottawa
CA
Agent
Gregg C Benson
Wolf Greenfield & Sacks P C
Assignee
University of Iowa Research Foundation
IA, US
IPC
C07H 21/02
A61K 45/00
View Original Source