07470537 is referenced by 26 patents and cites 58 patents.

The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides an adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.

Title
Adipose-derived stem cells and lattices
Application Number
10/740315
Publication Number
7470537 (B2)
Application Date
December 17, 2003
Publication Date
December 30, 2008
Inventor
Min Zhu
Los Angeles, 90034
CA, US
Hermann Peter Lorenz
Belmont, 94002
CA, US
Prosper Benhaim
Encino, 91436
CA, US
J William Futrell
Pittsburgh, 15238
PA, US
Ramón Llull
Mallorca, Balearic Isles, E-7320
ES
Adam J Katz
Charlottesville, 22911
VA, US
Marc H Hedrick
Encino, 91346
CA, US
Agent
Mandel & Adriano
IPC
C12N 5/00
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