A surgical instrument. The surgical instrument comprises a handle, a battery, a motor, and a lockout system. The handle comprises a primary portion and a grip portion. The grip portion is releasably connected to the primary portion. The battery is within the grip portion. The motor is in electrical communication with the battery. The lockout system is within the handle, and is structured and arranged to block connection of the grip portion to the primary portion after the grip portion is disconnected from the primary portion a predetermined number of times.