A partition system includes an internally-open partition frame having permanent and removable frame members forming multiple vertical and horizontal wireways, with both lay-in and feed-through wire routing. Utility support brackets are attachable for good wire management. The partition frame supports a wide variety of customizable and functional surface components, including a markerboard wall surface, a slatwall, a colored/covered wall surface, a wall surface including utility outlets, a transparent window. The partition frame includes continuous horizontal and vertical rows of slots that flexibly and adjustably support furniture accessories, such as a worksurface, at selected heights and locations along the partition system. Covers are provided that maintain a very high-quality appearance with uniform lines and gaps. Some covers include adjustable edge-mounted light seals for eliminating light leaks and unsightly areas. Further, the present partition system provides flexibility, customizability, rearrangeability, reconfigurability, and an intuitive assembly.