07421882 is referenced by 16 patents and cites 31 patents.

A method of diagnosing the health of an individual by collecting a breath sample from the individual and measuring the amount of each of a plurality of analytes in the sample. The amount of each analytes is measured by fitting a time response curve of a sample-evaluation fuel cell in which the fuel cell sample electrode is contacted with the sample with the analysis based on a function of standard time response curves for an equivalent fuel cell configuration obtained separately for each of the analytes on a fuel cell with equivalent construction as sample-evaluation fuel cell. Each of the plurality of analytes is generally indicative of an aspect of the individual's health. Suitable analytes include, for example, inorganic compounds as well as compositions that exhibit negative reduction reactions at least for a portion of the time response curve. In particular, acetone exhibits a negative potential/current peak when it is an analyte in a fuel cell in an sample electrode with a counter electrode exposed to oxygen, which may or may not be introduced in the form of air. Various forms of analysis to estimate acetone concentrations in the breath can be used.

Title
Breath-based sensors for non-invasive molecular detection
Application Number
11/305799
Publication Number
7421882 (B2)
Application Date
December 16, 2005
Publication Date
September 9, 2008
Inventor
Luke M Haverhals
Coralville
IA, US
Johna Leddy
Iowa City
IA, US
Agent
Foley & Lardner
Assignee
University of Iowa Research Foundation
IA, US
IPC
G01N 1/22
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