07371777 is referenced by 5 patents and cites 46 patents.

The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each represents 0 to 4; R1 to R6 are the same as or different from one another and each represents a hydrogen atom, a hydroxyl group, a cyano group, a halogen atom, etc.; A1 and A2 are the same as or different from each other and each represents a single bond, an oxygen atom, etc.; L, M and T each represent a single bond, an alkylene group having one to six carbon atoms, etc.; W represents a carboxyl group; the partial structure represented by the formula: represents a single bond or a double bond; X represents a single bond, an oxygen atom, —NRx1CQ1O—, etc.; Y represents Y1—Y2— (wherein Y1 represents a 5 to 14-membered aromatic ring having one to four substituents, etc.; and Y2 represents a single bond or a 5 to 14-membered aromatic ring); and the ring Z represents a 5 to 14-membered aromatic ring which have one to four substituents selected form the above-mentioned Group A, may have one or more hetero atoms and may be partially saturated.

Title
Cyclic compound and PPAR agonist
Application Number
10/486396
Publication Number
7371777 (B2)
Application Date
August 16, 2002
Publication Date
May 13, 2008
Inventor
Taro Hihara
Ibaraki
JP
Sadakazu Miyashita
Ibaraki
JP
Takashi Inoue
Ibaraki
JP
Kazuto Yamazaki
Ibaraki
JP
Hideki Yoshitomi
Ibaraki
JP
Shunji Kasai
Ibaraki
JP
Masanobu Shinoda
Ibaraki
JP
Eita Emori
Ibaraki
JP
Fumiyoshi Matsuura
Ibaraki
JP
Richard Clark
Ibaraki
JP
Agent
Birch Stewart Kolasch & Birch
Assignee
Eisai
JP
IPC
C07D 307/04
A61K 31/341
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