07365057 is referenced by 49 patents and cites 329 patents.

2′ and/or 3′ prodrugs of 1′, 2′, 3′ or 4′-branchednucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.

Title
infections
Modified 2′ and 3′-nucleoside prodrugs for treating
Application Number
11/5447
Publication Number
7365057 (B2)
Application Date
December 6, 2004
Publication Date
April 29, 2008
Inventor
Jean Pierre Sommadossi
Cambridge
MA, US
Gilles Gosselin
Monpellier
FR
Richard Storer
Folkstone
GB
Paola LaColla
Cagliari
IT
Agent
Jones Day
Assignee
Universita Degli Studi Di Cagliari
IT
Centre National de la Recherche Scientifique
FR
Idenix Pharmaceuticals
MA, US
IPC
A61K 31/70
A01N 43/04
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