07357940 is referenced by 10 patents and cites 27 patents.

Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymer release region comprises a graft copolymer, which further comprises a main chain and a plurality of side chains. One of (a) the main chain and (b) the side chains corresponds to a rubbery phase within the release region at ambient temperatures, while the other corresponds to a hard phase within the release layer at ambient temperatures. Typically, the graft copolymer will comprise one glass transition temperature below ambient temperature and another second glass transition temperature above ambient temperature. Also described are methods for forming the above graft copolymers, methods for administering a therapeutic agent to a patient using the above implantable or insertable medical devices, as well as methods for making the above devices.

Title
Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents
Application Number
10/632413
Publication Number
7357940 (B2)
Application Date
July 31, 2003
Publication Date
April 15, 2008
Inventor
Frederick H Strickler
Natick
MA, US
Robert E Richard
Wrentham
MA, US
Agent
Keum J Park Esq
David B Bonham Esq
Mayer & Williams PC
Assignee
Boston Scientific Scimed
MN, US
IPC
A61F 13/00
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