07297348 is referenced by 8 patents and cites 37 patents.

A drug delivery system that includes a hydrogel formed from cyclodextrin and an amphiphilic copolymer that includes an A polymer block comprising a poly(alkylene oxide) and a B polymer block comprising a poly(hydroxyalkanoate), and a therapeutically effective amount of at least one therapeutic agent intimately contained within the hydrogel. In one preferred embodiment of the invention, the A polymer block is poly(ethylene oxide) (PEO) and the B polymer block is poly[(R)-3-hydroxybutyrate] (PHB), and the copolymer is the triblock ABA copolymer PEO-PHB-PEO. A method of synthesizing the amphiphilic triblock copolymer is also provided.

Title
Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from
Application Number
10/624136
Publication Number
7297348 (B2)
Application Date
July 18, 2003
Publication Date
November 20, 2007
Inventor
Kam W Leong
Ellicott City
MD, US
Xiping Ni
Singapore
SG
Xu Li
Singapore
SG
Jun Li
Singapore
SG
Agent
Marcia S Kelbon
Assignee
Institute of Materials Research and Engineering
SG
Omeros Corporation
WA, US
IPC
A61K 9/14
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