07291497 is referenced by 273 patents and cites 63 patents.

The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.

Title
Medical device for analyte monitoring and drug delivery
Application Number
10/937872
Publication Number
7291497 (B2)
Application Date
September 10, 2004
Publication Date
November 6, 2007
Inventor
Chengwang Wang
Mountain View
CA, US
John Howard
Saratoga
CA, US
Shaunak Roy
San Mateo
CA, US
Elizabeth A Holmes
Palo Alto
CA, US
Agent
Wilson Sonsini Goodrich & Rosati
Assignee
Theranos
CA, US
IPC
A61F 13/00
C12M 1/34
G01N 15/06
G01N 33/53
C12Q 1/00
A61M 5/00
A61M 5/32
A61M 25/00
A61M 31/00
View Original Source