07279331 is referenced by 4 patents and cites 7 patents.

The present invention relates to methods of inducing differentiation of mammalian bone marrow stromal cells into neuronal cells by contacting marrow stromal cells with a neuronal differentiation-inducing compounds. Neuronal differentiation-inducing compounds of the invention include anti-oxidants such as, but not limited to, beta-mercaptoethanol, dimethylsulfoxide, butylated hydroxyanisole, butylated hydroxytoluene, ascorbic acid, dimethylfumarate, and n-acetylcysteine. Once induced to differentiate into neuronal cells, the cells can be used for cell therapy, gene therapy, or both, for treatment of diseases, disorders, or conditions of the central nervous system.

Title
Differentiation of bone marrow cells into neuronal cells and uses therefor
Application Number
10/213526
Publication Number
7279331 (B2)
Application Date
August 6, 2002
Publication Date
October 9, 2007
Inventor
Emily Schwarz
Chapel Hill
NC, US
Darwin J Prockop
New Orleans
LA, US
Dale L Woodbury
Piscataway
NJ, US
Ira B Black
Skillman
NJ, US
Agent
Seed IP Law Group PLLC
Assignee
University of Medicine and Dentistry of New Jersey
NJ, US
Philadelphia Health and Education Corporation
PA, US
IPC
C12N 5/08
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