07271315 is referenced by 71 patents and cites 22 patents.

Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from Schizochytrium, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.

Title
PUFA polyketide synthase systems and uses thereof
Application Number
11/452138
Publication Number
7271315 (B2)
Application Date
June 12, 2006
Publication Date
September 18, 2007
Inventor
William R Barclay
Boulder
CO, US
Jerry M Kuner
Longmont
CO, US
James H Flatt
Colorado Springs
CO, US
James G Metz
Longmont
CO, US
Agent
Sheridan Ross P C
Assignee
Martek Biosciences Corporation
MD, US
IPC
C12N 5/00
C12P 7/64
A01H 5/00
A01H 9/00
A01H 1/00
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