07244861 is referenced by 11 patents and cites 22 patents.

The present invention provides a medicament comprising a benzene compound useful as an insulin sensitizer, a salt thereof or a hydrate of them and a derivative of them as the active ingredient. Specifically, it provides a benzene compound represented by the following formula, a salt thereof or a hydrate of them. In the formula, X represents 1) a C6-10 aryl group which may have one or more substituents or 2) a 5- to 10-membered heteroaryl group which may have one or more substituents; Y represents a group represented by the formula: (in the above formulae, Ry1, Ry2 and Ry3 are the same as or different from one another and each represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, or a C3-7 cycloalkyl group) etc.; Z represents a group represented by the formula: (in the formula, m represents an integer of 0 to 2; Rz1, Rz2, Rz3 and Rz4 are the same as or different from one another and each represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C3-7 cycloalkyl group, a halogenated C1-6 alkyl group, a halogenated C1-6 alkoxy group etc.); and R1, R2, R3 and R4 are the same as or different from one another and each represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C3-7 cycloalkyl group etc.

Title
Benzene compound and salt thereof
Application Number
10/471254
Publication Number
7244861 (B2)
Application Date
March 27, 2002
Publication Date
July 17, 2007
Inventor
Taro Hihara
Ibaraki
JP
Sadakazu Miyashita
Ibaraki
JP
Takashi Inoue
Ibaraki
JP
Kazuto Yamazaki
Ibaraki
JP
Hideki Yoshitomi
Ibaraki
JP
Shunji Kasai
Ibaraki
JP
Richard Clark
Ibaraki
JP
Masanobu Shinoda
Ibaraki
JP
Eita Emori
Ibaraki
JP
Fumiyoshi Matsuura
Ibaraki
JP
Agent
Birch Stewart Kolasch & Birch
Assignee
Eisai
JP
IPC
C07C 227/00
C07C 229/00
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