07226978 is referenced by 556 patents and cites 253 patents.

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

Title
Techniques to improve polyurethane membranes for implantable glucose sensors
Application Number
10/153356
Publication Number
7226978 (B2)
Application Date
May 22, 2002
Publication Date
June 5, 2007
Inventor
Jason D McClure
San Diego
CA, US
Mark C Shults
Madison
WI, US
Rathbun K Rhodes
Madison
WI, US
Mark A Tapsak
San Diego
CA, US
Agent
Knobbe Martens Olson & Bear
Assignee
DexCom
CA, US
IPC
B01D 39/14
C08F 265/10
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