07223380 is referenced by 27 patents and cites 69 patents.

The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.

Title
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
Application Number
10/672763
Publication Number
7223380 (B2)
Application Date
September 26, 2003
Publication Date
May 29, 2007
Inventor
E Edmund Kim
Houston
TX, US
Dong Fang Yu
Houston
TX, US
Chun W Liu
Sugarland
TX, US
David J Yang
Sugarland
TX, US
Agent
Fulbright & Jaworski L
Assignee
Board of Regents The University of Texas System
TX, US
IPC
A61K 49/04
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