07220549 is referenced by 104 patents and cites 611 patents.

The invention provides methods for sequencing a nucleic acid comprising stabilizing a primer/target nucleic acid duplex on a substrate. Methods of the invention generally contemplate the use of a dual-anchored primer/target nucleic acid duplex, or a stabilizing molecule in a single molecule sequencing reaction.

Title
Stabilizing a nucleic acid for nucleic acid sequencing
Application Number
11/27165
Publication Number
7220549 (B2)
Application Date
December 30, 2004
Publication Date
May 22, 2007
Inventor
Philip Richard Buzby
Brockton
MA, US
Agent
Edwards Angell Palmer & Dodge
Thomas C Meyers
Assignee
Helicos Biosciences Corporation
MA, US
IPC
C12P 19/34
C12Q 1/68
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