07220430 is referenced by 9 patents and cites 14 patents.

The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent layers in the multilayered coating layer contain mutually different hydrophobic organic compound-water-soluble polymer mixtures; and, a method of producing a sustained release preparation, having a multilayered coating layer in which adjacent layers contain different hydrophobic organic compound-water-soluble polymer mixtures, which comprises spray-coating a solution containing a hydrophobic organic compound-water-soluble polymer mixture onto a drug-containing core substance, continuing to spray-coat a solution containing a different hydrophobic organic compound-water-soluble polymer mixture onto the resulting coating layer, and repeating this step.

Title
Sustained-release preparation and process for producing the same
Application Number
10/182239
Publication Number
7220430 (B2)
Application Date
January 26, 2001
Publication Date
May 22, 2007
Inventor
Masakazu Mizobe
Takatsuki
JP
Hiroyuki Yoshino
Suita
JP
Keigo Nagao
Kawanishi
JP
Kengo Ikegami
Nishinomiya
JP
Takashi Ishibashi
Sakai
JP
Agent
Birch Stewart Kolasch & Birch
Assignee
Tanabe Seiyaku
JP
IPC
A61K 9/42
A61K 9/30
A61K 9/28
A61K 9/22
A61K 9/24
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