07217856 is referenced by 75 patents and cites 15 patents.

Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.

Title
PUFA polyketide synthase systems and uses thereof
Application Number
10/965017
Publication Number
7217856 (B2)
Application Date
October 13, 2004
Publication Date
May 15, 2007
Inventor
James G Metz
Longmont
CO, US
Ross Zirkle
Longmont
CO, US
Craig A Weaver
Boulder
CO, US
Agent
Sheridan Ross P C
Assignee
Martek Biosciences Corporation
MD, US
IPC
C12P 7/64
C12N 5/00
C07H 21/04
A01H 1/00
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